Universal Health with Pharmaceutical Ingredients
It all started with a gift from the sun
Our origins can be traced back over 140 years when sweet foods were very highly valued, and we developed syrup from starch, a gift from the sun.
Our long history of respecting nature and expertise in biotechnology led to the world's first successful mass production of trehalose, which has been supporting potentially life-changing drug modalities and significantly impacting the pharmaceutical industry. We have committed to the integrated production of trehalose, from procurement of raw materials to manufacturing and advanced refining, to ensure a stable supply of safe, high-purity and low-endotoxin trehalose. We continue to innovate and expand the biopharmaceutical applications of trehalose.
Achieving Equitable Well-Being for All
Delivering Universal Health
Biopharmaceuticals have been a basis for new life-changing medicines and therapeutic treatments. They often encounter stability issues, such as degradation or aggregation during manufacturing and storage, requiring strict temperature control. These challenges have left the world facing difficulties in delivering viable medicines, vaccines, and essential healthcare, especially to areas with limited transport infrastructure and unstable utility supply.Utilizing our pharmaceutical ingredients, such as trehalose, in facilitating the storage and transport of medicines has been seen as playing an essential role in ensuring a stable global supply. Our innovative solutions are transforming the global health landscape, empowering communities, and bridging gaps.
With an unwavering dedication to well-being, we strive to ensure equitable access to quality healthcare for all.
One of the practical ways to store and deliver biopharmaceuticals is lyophilization. Saccharides, including trehalose, act as key excipients to stabilize large molecules that would otherwise be denatured during dehydration and freezing.
Our SOLBIOTE™ portfolio includes high-purity and low-endotoxin TREHALOSE SG and MALTOSE PH, providing solutions for biologics, vaccine, and cell-based therapeutics development. SOLBIOTE™ stabilizes proteins and nucleic acids and preserves the quality of antibody drugs and other products widely used to treat severe infectious diseases and cancer.
Benefits of SOLBIOTE™:
- Stabilizes higher-order protein structures during dehydration and freezing
- Prevents cells and liposomes from damage during freezing and thawing
- Suitable for parenteral use (low-endotoxin)
 | |||
| Grade | Injection Grade | ||
| Product Name | TREHALOSE SG | MALTOSE PH | |
| Purity | ≧99.0% (Trehalose) | ≧98.0% (Maltose) | |
| Endotoxin | ＜0.3 EU/g | ＜0.6 EU/g | |
| Application |
|
| |
| Packaging | 1kg/PE bag, 20kg/carton, 20kg/plastic container | 25kg/carton | |
| Regulatory Approval | JP | ||
| USP-NF | |||
| Ph. Eur. | |||
| CP | |||
| US DMF | Type IV | Type II | |
| China DMF | F20170000105(A) | F20200000041(I) | |
| Other | Kosher | ||
| Halal | |||
| Grade | Oral Grade | |||
|---|---|---|---|---|
| Product Name | TREHALOSE 100PH | PULLULAN | SUNMALT™-S | |
| Purity | ≧99.0% (Trehalose) | - | ≧92.0% (Maltose) | |
| Endotoxin | - | - | - | |
| Application |
|
|
| |
| Packaging | 20kg/carton | 10kg/carton | 20kg/paper bag | |
| Regulatory Approval | JP | |||
| USP-NF | ||||
| Ph. Eur. | ||||
| CP | ||||
| US DMF | ||||
| China DMF | ||||
| Other | Kosher | |||
| Halal | ||||
| ||
| Product Name | TREHALOSE SG | |
|---|---|---|
| Grade | Injection Grade | |
| Purity | ≧99.0% (Trehalose) | |
| Endotoxin | ＜0.3 EU/g | |
| Application | ||
| ||
| Packaging | ||
| 1kg/PE bag, 20kg/carton, 20kg/plastic container | ||
| Regulatory Approval | JP | |
| USP-NF | ||
| Ph. Eur. | ||
| CP | ||
| US DMF | Type IV | |
| China DMF | F20170000105(A) | |
| Other | Kosher | |
| Halal | ||
| SOLBIOTE™ | ||
| Product Name | MALTOSE PH | |
|---|---|---|
| Grade | Injection Grade | |
| Purity | ≧98.0% (Maltose) | |
| Endotoxin | ＜0.6 EU/g | |
| Application | ||
| ||
| Packaging | ||
| 25kg/carton | ||
| Regulatory Approval | JP | |
| USP-NF | ||
| Ph. Eur. | ||
| CP | ||
| US DMF | Type II | |
| China DMF | F20200000041(I) | |
| Other | Kosher | |
| Halal | ||
| Product Name | TREHALOSE 100PH | |
|---|---|---|
| Grade | Oral Grade | |
| Purity | ≧99.0% (Trehalose) | |
| Endotoxin | - | |
| Application | ||
| ||
| Packaging | ||
| 20kg/carton | ||
| Regulatory Approval | JP | |
| USP-NF | ||
| Ph. Eur. | ||
| CP | ||
| US DMF | ||
| China DMF | ||
| Other | Kosher | |
| Halal | ||
| Product Name | PULLULAN | |
|---|---|---|
| Grade | Oral Grade | |
| Purity | - | |
| Endotoxin | - | |
| Application | ||
| ||
| Packaging | ||
| 10kg/carton | ||
| Regulatory Approval | JP | |
| USP-NF | ||
| Ph. Eur. | ||
| CP | ||
| US DMF | ||
| China DMF | ||
| Other | Kosher | |
| Halal | ||
| Product Name | SUNMALT™-S | |
|---|---|---|
| Grade | Oral Grade | |
| Purity | ≧92.0% (Maltose) | |
| Endotoxin | - | |
| Application | ||
| ||
| Packaging | ||
| 20kg/paper bag | ||
| Regulatory Approval | JP | |
| USP-NF | ||
| Ph. Eur. | ||
| CP | ||
| US DMF | ||
| China DMF | ||
| Other | Kosher | |
| Halal | ||
Respecting Our Planet
Creating a prosperous future for both people and nature, we strive to improve greener and cleaner production that does not negatively impact the people involved or the natural environment, including:
- Utilization of naturally-derived raw materials, such as starch
- Manufacturing of natural ingredients using enzymes derived from soil microorganisms
- Reduction of CO2 emission during procurement and production processes
- Reduction of post-manufacturing waste
- Procurement of raw materials and resources
- We confirm with suppliers that raw material production (e.g. starch) does not involve deforestation or human rights violations.
- Product
manufacturing 
- Promoting energy conservation and reduction of CO2
- Using proper inventory control and manufacturing planning to reduce waste
- Using water resources efficiently
- Product
- Promotion of waste reduction and recycling
- We promote wastewater treatment to meet environmental standards and recycling of residues after disposal as compost and cement admixture.
For our dedication to sustainable manufacturing, human rights, and procurement, we have been awarded a Platinum rating by EcoVadis, a sustainability survey organization in France covering over 180 countries. Platinum is the highest rank, given to the top 1% of over 130,000 companies assessed.
We sincerely continue to commit sustainability and social responsibilities towards a better future of the people and the Earth.